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Top 5 · Vitamins & Minerals

Top 5 Best Vitamin D3 + K2 Supplements 2026

Vitamin D3 + K2 Supplements ranked on form, dose, third-party testing and value per unit of active ingredient.

Updated August 5, 20265 rankedNo paid placements

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Full rankings

1
Natural Factors, Vitamin D3 & K2, 25 mcg (1,000 IU) & 120 mcg - Ranked #1 Vitamin D3 + K2 Supplements
Best overall

Natural Factors, Vitamin D3 & K2, 25 mcg (1,000 IU) & 120 mcg

Its weighted score is 8.15/10. ISURA certification, oil delivery and MK-7 outweigh its middling active-ingredient cost and below-trial doses.

ISURA independently certifies finished-product potency, label integrity and contaminant screeningProvides 120 mcg of the longer-retained MK-7 form per softgelUses palm- and coconut-derived MCT oil as a carrier for both fat-soluble vitaminsThe gelatin shell, beeswax and caramel color make it unsuitable for vegansIts 120 mcg MK-7 dose is two-thirds of the 180 mcg daily amount used in a published three-year human trial
8.2/ 10
$20.97at iHerbCheck priceRead full review
2
Thorne, Vitamin D + K2 Liquid, 1 fl oz (30 ml) - Ranked #2 Vitamin D3 + K2 Supplements
Best premium

Thorne, Vitamin D + K2 Liquid, 1 fl oz (30 ml)

Its weighted score is 8.05/10. NSF certification and exceptional active-unit value nearly earn first place, but the MK-4 dose is far below the amount used in published MK-4 trials.

NSF/ANSI 173 Contents Certified, with the product present in NSF's current official listingMCT-oil liquid avoids a dry capsule and permits dosing in two-drop incrementsCosts approximately $0.057 per labeled serving and $0.028 per 100 mcg of K2The 200 mcg MK-4 serving is 225 times lower than the 45 mg daily dose used in published MK-4 trialsThe label does not disclose whether its D3 source is lanolin-derived or vegan
8.1/ 10
$34at iHerbCheck priceRead full review
3
Nordic Naturals, Vitamin D3 + K2, Great Orange, 60 Soft Gels - Ranked #3 Vitamin D3 + K2 Supplements

Nordic Naturals, Vitamin D3 + K2, Great Orange, 60 Soft Gels

Its weighted score is 7.40/10. The research-comparable D3 dose, MK-7 and olive-oil delivery are strong, but its verification evidence is weaker than the two higher-ranked products.

Provides the same 2,000 IU daily D3 dose used in the large VITAL trialUses longer-retained MK-7 rather than MK-4Supplies an organic extra-virgin olive-oil carrierThe gelatin softgel is not veganThe label states third-party purity testing, but no public product-specific certificate of analysis was identified
7.4/ 10
$16.96at iHerbCheck priceRead full review
4
MRM Nutrition, Vegan Vitamin D3 & K2, 60 Vegan Capsules - Ranked #4 Vitamin D3 + K2 Supplements

MRM Nutrition, Vegan Vitamin D3 & K2, 60 Vegan Capsules

Its weighted score is 6.45/10. It is the strongest vegan option in this group on source disclosure and value, but lacks an oil carrier and finished-product potency certification.

Uses explicitly disclosed lichen-derived VegaDELight D3 and carries Certified Vegan statusProvides MK-7 with a 2,500 IU D3 dose that is close to the 2,000 IU VITAL doseContains only rice flour, a cellulose capsule and tapioca dextrin as other ingredientsThe dry capsule contains no oil carrierIts 80 mcg MK-7 dose is about 44% of the 180 mcg daily amount used in the cited three-year trial
5
Doctor's Best, Natural Vitamin K2 MK-7 plus D3, 180 mcg, 60 Veggie Caps - Ranked #5 Vitamin D3 + K2 Supplements

Doctor's Best, Natural Vitamin K2 MK-7 plus D3, 180 mcg, 60 Veggie Caps

Its weighted score is 6.25/10. MenaQ7 and a research-comparable MK-7 dose are meaningful advantages, but limited verification, dry delivery and a long excipient list keep it fifth.

Uses branded MenaQ7 MK-7 sourced from fermented chickpeasIts 180 mcg K2 serving matches the daily MK-7 dose used in the cited three-year human trialFully discloses both active amounts without a proprietary blendThe dry capsule has no oil carrier and contains maltodextrin, sucrose, starch and several processing ingredientsNo USP, NSF or public product-specific certificate was identified, and the cost is $0.40 per serving
6.3/ 10
$23.99at iHerbCheck priceRead full review
Side by side

How they scored

ProductThird-Party Testing · 30%Form & Bioavailability · 25%Dose vs Research · 20%Label Transparency · 15%Value · 10%ScorePrice
1Natural Factors, Vitamin D3 & K2, 25 mcg (1,000 IU) & 120 mcg
997868.2$20.97
2Thorne, Vitamin D + K2 Liquid, 1 fl oz (30 ml)
107410108.1$34
3Nordic Naturals, Vitamin D3 + K2, Great Orange, 60 Soft Gels
598977.4$16.96
4MRM Nutrition, Vegan Vitamin D3 & K2, 60 Vegan Capsules
387986.5
5Doctor's Best, Natural Vitamin K2 MK-7 plus D3, 180 mcg, 60 Veggie Caps
388776.3$23.99

Specs Comparison

#1#2#3#4#5
Product
Natural Factors, Vitamin D3 & K2, 25 mcg (1,000 IU) & 120 mcg specs - Top 5 Vitamin D3 + K2 Supplements
Natural Factors, Vitamin D3 & K2, 25 mcg (1,000 IU) & 120 mcg
Thorne, Vitamin D + K2 Liquid, 1 fl oz (30 ml) specs - Top 5 Vitamin D3 + K2 Supplements
Thorne, Vitamin D + K2 Liquid, 1 fl oz (30 ml)
Nordic Naturals, Vitamin D3 + K2, Great Orange, 60 Soft Gels specs - Top 5 Vitamin D3 + K2 Supplements
Nordic Naturals, Vitamin D3 + K2, Great Orange, 60 Soft Gels
MRM Nutrition, Vegan Vitamin D3 & K2, 60 Vegan Capsules specs - Top 5 Vitamin D3 + K2 Supplements
MRM Nutrition, Vegan Vitamin D3 & K2, 60 Vegan Capsules
Doctor's Best, Natural Vitamin K2 MK-7 plus D3, 180 mcg, 60 Veggie Caps specs - Top 5 Vitamin D3 + K2 Supplements
Doctor's Best, Natural Vitamin K2 MK-7 plus D3, 180 mcg, 60 Veggie Caps
BrandNatural FactorsThorneNordic NaturalsMRM NutritionDoctor's Best
D3 Per Serving25 mcg (1,000 IU)25 mcg (1,000 IU)50 mcg (2,000 IU)62.5 mcg (2,500 IU)25 mcg (1,000 IU)
K2 Per Serving120 mcg200 mcg90 mcg80 mcg180 mcg
K2 FormMK-7 from natto beanMK-4 (menatetrenone)MK-7 (menaquinone-7)MK-7 (menaquinone-7)MK-7 from fermented chickpeas
K2 BrandNot stated on labelNot stated on labelNot stated on labelNot stated on labelMenaQ7
Delivery FormOil-based gelatin softgel with MCT oilMCT-oil liquid; two drops per servingOlive-oil-based gelatin softgelDry cellulose vegan capsuleDry hypromellose vegetarian capsule
D3 SourceCholecalciferol; source not disclosed on iHerb labelCholecalciferol; source not disclosed on iHerb labelCholecalciferol; source not disclosed on iHerb labelLichen-derived VegaDELight; Certified VeganCholecalciferol; source not disclosed on iHerb label
Third-Party VerificationISURA Verified Clean certificationNSF/ANSI 173 Contents CertifiedLabel states 3rd Party Purity Tested and IGEN Non-GMO Tested; no public product-specific COA identifiedCertified Vegan and Non-GMO Project Verified; neither verifies D3/K2 potencyNo recognized finished-product certification or public product-specific COA identified
Active Cost$0.350 per 1,000 IU D3; $0.291 per 100 mcg K2$0.057 per 1,000 IU D3; $0.028 per 100 mcg K2$0.141 per 1,000 IU D3; $0.314 per 100 mcg K2$0.091 per 1,000 IU D3; $0.283 per 100 mcg K2$0.400 per 1,000 IU D3; $0.222 per 100 mcg K2
Price$20.97$34$16.96$23.99

How we ranked them

Start with the Supplement Facts panel, not the front-label dose or bottle count. Compare the amount per serving and confirm whether one serving is one capsule, multiple capsules or several drops. For vitamin D, every product here uses D3, or cholecalciferol. The NIH lists 600 IU daily as the adult RDA through age 70 and 800 IU after age 70, while the large VITAL human trial used 2,000 IU of D3 per day. These are comparison anchors, not proof that 2,000 IU is the correct personal dose. The adult tolerable upper intake level is 4,000 IU daily from all sources, so a 5,000 IU product should not automatically be considered better. Total intake and measured 25-hydroxyvitamin D should guide individualized decisions with a qualified clinician. For K2, distinguish MK-7 from MK-4. Human pharmacokinetic work indicates that MK-7 is retained in circulation longer than MK-4, making microgram once-daily formulas practical. A three-year MK-7 trial used 180 mcg daily. By contrast, published MK-4 trials commonly used 45 mg daily, or 45,000 mcg, so a product containing 200 mcg of MK-4 should not be described as matching that research dose. Branded forms such as MenaQ7 identify a standardized ingredient source, but the ingredient trademark does not independently certify the finished bottle. Delivery form also matters because D3 and K2 are fat-soluble. Oil-based drops and softgels supply a lipid carrier directly. A dry capsule can still be a reasonable choice when its directions specify taking it with food, but buyers should not assume that a vegetable capsule contains oil. Likewise, a vegetarian capsule does not prove the D3 is vegan: strict vegans should look for an explicitly disclosed lichen-derived D3 source and a vegan certification. Give the highest testing credit to finished-product certifications such as USP or NSF, or to a publicly available product-specific certificate of analysis. A cGMP facility, Non-GMO verification or an unspecified third-party-tested statement is not equivalent to independent confirmation of the active amounts. ISURA certification is relevant because its published standard covers finished-product potency, label integrity and contaminant screening. Check transparency for the exact K2 form, D3 source, all active doses, allergens and every excipient. Avoid proprietary blends, undisclosed K forms, unexplained high-potency D3 and products that substitute capsule count for serving count. Common mistakes include ranking solely by price per bottle, assuming more D3 is always preferable, treating MK-4 and MK-7 doses as interchangeable, and overlooking anticoagulant interactions. Vitamin K intake requires particular care for people using warfarin or another vitamin-K-antagonist medication.

We rank on third-party testing (30%), form and bioavailability (25%), dose versus published human research (20%), label transparency (15%) and value per unit of active ingredient (10%). Specifications are taken from each product's supplement facts panel on its iHerb listing, and certification claims are checked against the certifying body's directory where one is published. We do not test products ourselves, and nothing here is medical advice.

Third-Party Testing

Independent certification or a published certificate of analysis

30%
Form & Bioavailability

Whether the chemical form is the well-absorbed one

25%
Dose vs Research

Per-serving dose versus doses used in published human trials

20%
Label Transparency

Full per-ingredient disclosure and minimal fillers

15%
Value

Cost per unit of active ingredient

10%
Learn more about how we rank

Questions, answered

Is MK-7 better absorbed than MK-4?
MK-7 is retained in circulation longer than MK-4 in human pharmacokinetic research, which is why many once-daily products use MK-7. The doses are not interchangeable: a major MK-7 trial used 180 mcg daily, while published MK-4 trials commonly used 45 mg daily.
How much D3 and K2 should a buyer look for?
For comparison, the adult vitamin D RDA is 600 IU through age 70 and 800 IU after age 70, the VITAL trial used 2,000 IU daily, and the adult tolerable upper intake level is 4,000 IU daily from all sources. A three-year MK-7 trial used 180 mcg daily, but there is no universally established optimal K2 supplement dose; personal D3 decisions should account for total intake, measured 25-hydroxyvitamin D and professional guidance.
Does an oil-based softgel or liquid matter?
D3 and K2 are fat-soluble. An oil-based softgel or liquid supplies fat in the product itself, whereas a dry capsule depends more on following the label direction to take it with food, preferably a meal containing some fat.
Who should be especially cautious with D3 + K2 supplements?
Vitamin K can interact seriously with warfarin and other vitamin-K-antagonist anticoagulants, so changes in supplemental or dietary vitamin K require clinician oversight. Buyers should also add together D3 from every supplement rather than evaluating a combination product in isolation.