Thorne Whey Protein Isolate Vanilla vs Dymatize ISO100 Hydrolyzed Whey Protein Isolate
Thorne Whey Protein Isolate Vanilla (#2, best premium) vs Dymatize ISO100 Hydrolyzed Whey Protein Isolate (#3, best value): in our Whey Protein Powders scoring the Thorne Whey Protein Isolate Vanilla totals 7.6/10 and the Dymatize ISO100 Hydrolyzed Whey Protein Isolate 7.4/10.
We may earn a commission when you buy through our links. Prices and availability shown are accurate as of Mar 8, 2026 and are subject to change; the merchant's price at purchase applies.
TopsFive comparison scores
Side by side
| Thorne Whey Protein Isolate Vanilla | Dymatize ISO100 Hydrolyzed Whey Protein Isolate | |
|---|---|---|
| Price | — | — |
| Protein | 21g per scoop | 25g per scoop |
| Type | Whey protein isolate | Hydrolyzed whey isolate |
| Servings | 30 | 71 |
| Testing | NSF Certified for Sport | — |
| Extras | Bromelain + papain enzymes | — |
| Calories | — | 110 |
| BCAAs | — | 5.5g (2.7g leucine) |
How they differ in real use
Built from our whey protein scoring, each product's published specifications, and verified owner feedback — not hands-on testing.
Both the Thorne Whey Protein Isolate Vanilla and the Dymatize ISO100 Hydrolyzed Whey Protein Isolate made our Top 5 Whey Protein Powders, at #2 (best premium) and #3 (best value). NSF Certified for Sport with explicit banned-substance testing—trusted by pro athletes. Added digestive enzymes (bromelain, papain) aid absorption, but only 30 servings makes it the lowest protein-per-dollar. Best protein-per-dollar (~26.15 g/$) with hydrolyzed whey isolate for rapid absorption. 5.5g BCAAs including 2.7g leucine per serving and 4.5 stars from 37,000+ ratings—but no third-party certification visible on Amazon.
We score whey protein powders on Protein Quality (35%), Third-Party Testing (25%), Taste & Mixability (20%), Ingredient Quality (10%) and Value (10%). On that basis the Thorne Whey Protein Isolate Vanilla totals 7.6 out of 10 and the Dymatize ISO100 Hydrolyzed Whey Protein Isolate 7.4. The widest gap is Third-Party Testing, where the Thorne Whey Protein Isolate Vanilla scores 10 against 2 for the Dymatize ISO100 Hydrolyzed Whey Protein Isolate — purity verification. Value also separates them: 10 for the Dymatize ISO100 Hydrolyzed Whey Protein Isolate versus 2 for the Thorne Whey Protein Isolate Vanilla. The Dymatize ISO100 Hydrolyzed Whey Protein Isolate claws back ground on Protein Quality and Taste & Mixability.
On paper, the specifications that actually differ: Protein — 21g per scoop on the Thorne Whey Protein Isolate Vanilla versus 25g per scoop on the Dymatize ISO100 Hydrolyzed Whey Protein Isolate; Type — Whey protein isolate on the Thorne Whey Protein Isolate Vanilla versus Hydrolyzed whey isolate on the Dymatize ISO100 Hydrolyzed Whey Protein Isolate; Servings — 30 on the Thorne Whey Protein Isolate Vanilla versus 71 on the Dymatize ISO100 Hydrolyzed Whey Protein Isolate.
Check current pricing at the merchant links below. Owners praise the Thorne Whey Protein Isolate Vanilla for NSF Certified for Sport and tested for banned substances; the most common complaint is only 30 servings per container. Owners praise the Dymatize ISO100 Hydrolyzed Whey Protein Isolate for best protein-per-dollar in the group and hydrolyzed for fast absorption; the most common complaint is no NSF/third-party certification on Amazon page.
Thorne Whey Protein Isolate Vanilla
- NSF Certified for Sport
- Tested for banned substances
- Whey isolate with digestive enzymes
- Complete essential amino acid profile
- Only 30 servings per container
- Low protein-per-dollar (~10.77 g/$)
- Contains cane sugar, gums, stevia
Dymatize ISO100 Hydrolyzed Whey Protein Isolate
- Best protein-per-dollar in the group
- Hydrolyzed for fast absorption
- 5.5g BCAAs / 2.7g leucine per serving
- 4.5 stars (37,000+ ratings)
- No NSF/third-party certification on Amazon page
- Contains sucralose and soy lecithin
- Artificial flavors
Which should you buy?
The Thorne Whey Protein Isolate Vanilla is the better fit for tested/pro athletes and NSF Certified for Sport needs — it is the higher-scoring pick here, chiefly for Third-Party Testing and Ingredient Quality. The Dymatize ISO100 Hydrolyzed Whey Protein Isolate is the better fit for value seekers wanting isolate quality and post-workout recovery, and the stronger choice if Value and Protein Quality matter more to you than the overall score. The Thorne Whey Protein Isolate Vanilla is a poor fit for budget shoppers; the Dymatize ISO100 Hydrolyzed Whey Protein Isolate is a poor fit for those requiring third-party certification.
Choose the Thorne Whey Protein Isolate Vanilla if
- Tested/pro athletes
- NSF Certified for Sport needs
- Easy digestion priority
Skip it if
- Budget shoppers
- High volume users
Choose the Dymatize ISO100 Hydrolyzed Whey Protein Isolate if
- Value seekers wanting isolate quality
- Post-workout recovery
- Lactose-sensitive users
Skip it if
- Those requiring third-party certification
- Artificial sweetener avoiders
Common questions
Is the Thorne Whey Protein Isolate Vanilla better than the Dymatize ISO100 Hydrolyzed Whey Protein Isolate?
In our Whey Protein Powders ranking the Thorne Whey Protein Isolate Vanilla scores higher overall, 7.6 to 7.4, with the biggest advantage in Third-Party Testing. The Dymatize ISO100 Hydrolyzed Whey Protein Isolate is stronger on Value and Protein Quality, so it is the better pick if those matter most to you.
What is the main difference between the Thorne Whey Protein Isolate Vanilla and the Dymatize ISO100 Hydrolyzed Whey Protein Isolate?
The headline spec difference is Protein: 21g per scoop on the Thorne Whey Protein Isolate Vanilla versus 25g per scoop on the Dymatize ISO100 Hydrolyzed Whey Protein Isolate. In use, the gap that matters most is Third-Party Testing (10 vs 2 in our scoring): purity verification.

